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Salmeterol

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Salmeterol Related Impurity-8
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Salmeterol Related Impurity-8

  • CAT Number DCTI-C-211
  • CAS Number NA
  • Molecular Formula C26H38O2
  • Molecular Weight 382.59
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Salmeterol Related Impurity-9
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Salmeterol Related Impurity-9

  • CAT Number DCTI-C-212
  • CAS Number NA
  • Molecular Formula C29H46ClNO2 (HCl Salt) C29H45NO2 (Free base)
  • Molecular Weight 476.14 (HCl Salt) 439.68 (Free base)
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References
FAQ's

References

  1. Skidmore, Ian Frederick; Lunts, Lawrence Henry Charles; Finch, Harry; Naylor, Alan, Phenethanolamine derivatives, Glaxo Group Ltd., United Kingdom, GB2140800A, December 5, 1984
  2. Kim, Kyeong Ho; Yun, Hyeong Won; Kim, Hyun Ju; Park, Hyun Ji; Choi, Pok Wah, Coupled column chromatography in chiral separation of salmeterol, Archives of Pharmacal Research Volume: 21, Issue: 2, Pages: 212-216, 1998

Frequently Asked Questions

Methods such as gradient Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) and preparative HPLC can detect impurities in Salmeterol.

Yes, impurities in Salmeterol can impact patient safety. Depending on their nature and concentration, contaminants can cause adverse effects or reduce the efficacy of the medication.

Methanol achieves optimal solubility and separation of Salmeterol impurities. However, the choice of solvent depends on the specific impurity analyzed and the analytical technique employed.

Salmeterol impurities should be stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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