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Salmeterol

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4,4′-(1,4-phenylene)bis(butan-1-ol)

  • CAT Number DCTI-C-550
  • CAS Number 21240-37-9
  • Molecular Formula C14H22O2
  • Molecular Weight 222.33
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6-Amino-1-(4-(benzyloxy)-3-(hydroxymethyl)phenyl)hexan-1-ol
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6-Amino-1-(4-(benzyloxy)-3-(hydroxymethyl)phenyl)hexan-1-ol

  • CAT Number DCTI-C-811
  • CAS Number NA
  • Molecular Formula C20H27NO3
  • Molecular Weight 329.44
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Alpha-Hydroxy salmeterol
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Alpha-Hydroxy salmeterol

  • CAT Number DCTI-C-667
  • CAS Number 21333-02-02
  • Molecular Formula C25H37NO5
  • Molecular Weight 431.57
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Benzyl 2-(benzyloxy)benzoate
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Benzyl 2-(benzyloxy)benzoate

  • CAT Number DCTI-C-508
  • CAS Number 14389-87-8
  • Molecular Formula C21H18O3
  • Molecular Weight 318.37
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Benzyl 5-acetyl-2-(benzyloxy)benzoate
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Benzyl 5-acetyl-2-(benzyloxy)benzoate

  • CAT Number DCTI-C-517
  • CAS Number 1292299-06-9
  • Molecular Formula C23H20O4
  • Molecular Weight 360.41
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Benzylated amino methyl impurity of SAM-V
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Benzylated amino methyl impurity of SAM-V

  • CAT Number DCTI-C-595
  • CAS Number NA
  • Molecular Formula C15H18ClNO2 (HCl Salt) C15H17NO2 (Free base)
  • Molecular Weight 279.76 (HCl Salt) 243.31 (Free base)
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Dimethyl-4-(benzyloxy)isopthalate
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Dimethyl-4-(benzyloxy)isopthalate

  • CAT Number DCTI-C-816
  • CAS Number 63295-94-3
  • Molecular Formula C17H16O5
  • Molecular Weight 300.31
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Salmeterol EP Impurity D

  • CAT NUMBER DCTI-C-2983
  • CAS NUMBER 1391052-04-2
  • MOLECULAR FORMULA C34H47NO7
  • MOLECULAR WEIGHT 581.75
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Salmeterol EP Impurity E

  • CAT NUMBER DCTI-C-3222
  • CAS NUMBER 108928-81-0
  • MOLECULAR FORMULA C25H37NO4
  • MOLECULAR WEIGHT 415.57
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References
FAQ's

References

  1. Skidmore, Ian Frederick; Lunts, Lawrence Henry Charles; Finch, Harry; Naylor, Alan, Phenethanolamine derivatives, Glaxo Group Ltd., United Kingdom, GB2140800A, December 5, 1984
  2. Kim, Kyeong Ho; Yun, Hyeong Won; Kim, Hyun Ju; Park, Hyun Ji; Choi, Pok Wah, Coupled column chromatography in chiral separation of salmeterol, Archives of Pharmacal Research Volume: 21, Issue: 2, Pages: 212-216, 1998

Frequently Asked Questions

Methods such as gradient Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) and preparative HPLC can detect impurities in Salmeterol.

Yes, impurities in Salmeterol can impact patient safety. Depending on their nature and concentration, contaminants can cause adverse effects or reduce the efficacy of the medication.

Methanol achieves optimal solubility and separation of Salmeterol impurities. However, the choice of solvent depends on the specific impurity analyzed and the analytical technique employed.

Salmeterol impurities should be stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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