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Isavuconazole

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Isavuconazonium chloride(diasteriomer-1)

  • CAT NUMBER DCTI-C-2271
  • CAS NUMBER NA
  • MOLECULAR FORMULA C35H35F2N8O5S+(FREE BASE); C35H36Cl2F2N8O5S (CHLORIDE SALT)
  • MOLECULAR WEIGHT 717.77(free base); 789.69(chloride salt)
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Isavuconazonium chloride(diasteriomer-2)

  • CAT NUMBER DCTI-C-2272
  • CAS NUMBER 2169911-47-9
  • MOLECULAR FORMULA C35H35F2N8O5S+(FREE BASE) C35H36Cl2F2N8O5S (CHLORIDE SALT)
  • MOLECULAR WEIGHT 717.77(free base) 789.69(chloride salt)
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Isavuconazonium chloride(enantiomer)

  • CAT NUMBER DCTI-C-2273
  • CAS NUMBER NA
  • MOLECULAR FORMULA C35H35F2N8O5S+(FREE BASE) C35H36Cl2F2N8O5S(CHLORIDE SALT)
  • MOLECULAR WEIGHT 717.77(free base) 789.69(chloride salt)
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Isotope of Oxazine Imp of Isavuconazole

  • CAT NUMBER DCTI-C-2860
  • CAS NUMBER NA
  • MOLECULAR FORMULA C8H5D3N2O2
  • MOLECULAR WEIGHT 167.18
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References
FAQ's

References

  1. Fukuda, Hiroshi; Hayase, Tadakatsu; Mizuguchi, Eisaku; Shimma, Nobuo; Ohwada, Jun; Oikawa, Nobuhiro; Sakaitani, Masahiro; Tsukazaki, Masao; Umeda, Isao, N-Substituted Carbamoyloxyalkyl-Azolium Derivatives, F. Hoffmann-La Roche A.-G., Switzerland, EP1280795B1, March 23, 2005
  2. Fatiguso, Giovanna; Favata, Fabio; Zedda, Ilaria; De Nicolo, Amedeo; Cusato, Jessica; Avataneo, Valeria; Di Perri, Giovanni; D'Avolio, Antonio, A simple high performance liquid chromatography-mass spectrometry method for Therapeutic Drug Monitoring of Isavuconazole and four other antifungal drugs in human plasma samples, Journal of Pharmaceutical and Biomedical Analysis, Volume: 145, Pages: 718-724, 2017

Frequently Asked Questions

Impurities in Isavuconazole are identified using analytical techniques such as chromatography, spectroscopy, and mass spectrometry. Comparison with reference standards or known impurities aids in identification.

Impurities in Isavuconazole are tested and monitored throughout the synthesis. Regular testing ensures compliance with regulatory guidelines and maintains the quality of the medication.

Quantification of impurities in Isavuconazole uses validated analytical methods. Calibration curves are generated using known reference standards to determine their concentration.

The recommendation is to store Isavuconazole impurities at a controlled room temperature, within 2-8 °C.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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