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Isavuconazole
References
FAQ's
References
- Fukuda, Hiroshi; Hayase, Tadakatsu; Mizuguchi, Eisaku; Shimma, Nobuo; Ohwada, Jun; Oikawa, Nobuhiro; Sakaitani, Masahiro; Tsukazaki, Masao; Umeda, Isao, N-Substituted Carbamoyloxyalkyl-Azolium Derivatives, F. Hoffmann-La Roche A.-G., Switzerland, EP1280795B1, March 23, 2005
- Fatiguso, Giovanna; Favata, Fabio; Zedda, Ilaria; De Nicolo, Amedeo; Cusato, Jessica; Avataneo, Valeria; Di Perri, Giovanni; D'Avolio, Antonio, A simple high performance liquid chromatography-mass spectrometry method for Therapeutic Drug Monitoring of Isavuconazole and four other antifungal drugs in human plasma samples, Journal of Pharmaceutical and Biomedical Analysis, Volume: 145, Pages: 718-724, 2017
Frequently Asked Questions
How are Isavuconazole impurities identified?
Impurities in Isavuconazole are identified using analytical techniques such as chromatography, spectroscopy, and mass spectrometry. Comparison with reference standards or known impurities aids in identification.
How frequently are Isavuconazole impurities tested and monitored?
Impurities in Isavuconazole are tested and monitored throughout the synthesis. Regular testing ensures compliance with regulatory guidelines and maintains the quality of the medication.
How are Isavuconazole impurities quantified?
Quantification of impurities in Isavuconazole uses validated analytical methods. Calibration curves are generated using known reference standards to determine their concentration.
How should Isavuconazole impurities be stored in terms of temperature?
The recommendation is to store Isavuconazole impurities at a controlled room temperature, within 2-8 °C.
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