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Varenicline

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Varenicline ortho-Diamino Impurity

  • CAT NUMBER DCTI-C-2641
  • CAS NUMBER 230615-69-7
  • MOLECULAR FORMULA C13H14F3N3O
  • MOLECULAR WEIGHT 285.27
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Varenicline ortho-Dinitro Impurity

  • CAT NUMBER DCTI-C-2639
  • CAS NUMBER 230615-59-5
  • MOLECULAR FORMULA C13H10F3N3O5
  • MOLECULAR WEIGHT 345.23
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Varenicline tartrate adduct

  • CAT NUMBER DCTI-C-2753
  • CAS NUMBER 2306217-15-0
  • MOLECULAR FORMULA C17H17N3O5
  • MOLECULAR WEIGHT 343.33
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References
FAQ's

References

  1. Coe, Jotham Wadsworth; Brooks, Paige Roanne Palmer, Aryl Fused Azapolycyclic Compounds, Pfizer Products Inc., EP1044189B1, February 13, 2008
  2. Satheesh, B.; Kumarpulluru, S.; Raghavan, V.; Saravanan, D., UPLC separation and quantification of related substances of varenicline tartrate tablet, Acta Chromatographica, Volume: 22, Issue: 2, Pages: 207-218, 2010

Frequently Asked Questions

HPLC separates impurities based on their chemical and physical properties, such as molecular weight, polarity, and charge. The separated impurities are then detected using a UV detector or a mass spectrometer.

Mass spectrometry is a sensitive technique that can detect and quantify impurities in Varenicline at low levels. It provides information on the molecular weight and structure of the impurities that helps in their identification and characterization.

Methanol or Acetonitrile is a solvent used in analyzing many impurities in Varenicline.

Varenicline impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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