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High-performance liquid chromatography (HPLC) and LCMS/ MS are employed to separate and analyze the impurities of Valsartan.
Impurities found in Valsartan can be classified into several categories, which include process-related contaminants, degradation products, residual solvents, and genotoxic impurities.
Valsartan impurities can change over time, influenced by storage conditions, exposure to light, and elevated temperatures.
The recommendation is to store Valsartan impurities at room temperature, within 2-8 °C.
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