Pemetrexed

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Pemetrexed EP Imp-E

  • CAT Number DCTI-C-389
  • CAS Number NA
  • Molecular Formula C20H19N5Na2O6
  • Molecular Weight 471.38

Pemetrexed EP Impurity A

  • CAT Number DCTI-C-158
  • CAS Number 869791-42-4
  • Molecular Formula C21H23N5O6
  • Molecular Weight 441.44

Pemetrexed EP Impurity-D

  • CAT Number DCTI-C-544
  • CAS Number 144051-68-3
  • Molecular Formula C25H28N6O9
  • Molecular Weight 556.53

Pemetrexed Impurity B

  • CAT Number DCTI-C-203
  • CAS Number NA
  • Molecular Formula C40H40N10O13
  • Molecular Weight 868.82

Pemetrexed Impurity C

  • CAT Number DCTI-C-204
  • CAS Number NA
  • Molecular Formula C40H40N10O13
  • Molecular Weight 868.82

Pemetrexed Oxidative Dimers (mixture of isomers B&C)

  • CAT NUMBER DCTI-C-2267
  • CAS NUMBER 1644286-34-9 (free acid)
  • MOLECULAR FORMULA C40H40N10O13(free acid); C40H52N14O13 (ammonium salt)
  • MOLECULAR WEIGHT 868.82 (free acid); 936.94 (ammonium salt)

Pemetrexed α-Dipeptide Impurity

  • CAT Number DCTI-C-463
  • CAS Number 883553-87-5
  • Molecular Formula C25H28N6O9
  • Molecular Weight 556.53

PMD acid Butem Impurity

  • CAT Number DCTI-C-444
  • CAS Number 240407-06-1
  • Molecular Formula C12H14O3
  • Molecular Weight 206.24

PMD acid oxidation Impurity

  • CAT Number DCTI-C-590
  • CAS Number 193265-47-3
  • Molecular Formula C15H14N4O4
  • Molecular Weight 314.3
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References
FAQ's

Frequently Asked Questions

During the development and validation of analytical methods, potential impurities in Pemetrexed evaluate the specificity, sensitivity, and selectivity to ensure impurities' accurate identification, quantification, and control following regulatory guidelines and standards.

Pemetrexed's stability and shelf life might be affected by impurities, which could eventually influence the drug's effectiveness and dependability.

Pemetrexed impurities are recorded and supported in the medication's specifications through comprehensive analytical testing, validation data, and documentation of impurity profiles, limits, and control measures to ensure compliance with regulatory guidelines.

Pemetrexed impurities are stored at a regulated room temperature of 2-8°C or as specified on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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