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Palbociclib

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Palbociclib Impurity 6

  • CAT NUMBER DCTI-C-2113
  • CAS NUMBER NA
  • MOLECULAR FORMULA C26H35N7O2
  • MOLECULAR WEIGHT 477.61
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Palbociclib Impurity 8

  • CAT NUMBER DCTI-C-2122
  • CAS NUMBER NA
  • MOLECULAR FORMULA C41H59N7O8
  • MOLECULAR WEIGHT 777.96
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Palbociclib Impurity A

  • CAT NUMBER DCTI-C-2372
  • CAS NUMBER 1956322-95-4 (HCl salt); 1082876-26-3(Free Base)
  • MOLECULAR FORMULA Free Base: C9H14N4; HCl Salt: C9H15ClN4
  • MOLECULAR WEIGHT Free Base: 178.24; HCl Salt: 214.70
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Palbociclib Impurity C

  • CAT NUMBER DCTI-C-2680
  • CAS NUMBER 2624141-94-0
  • MOLECULAR FORMULA C25H31N7O2
  • MOLECULAR WEIGHT 461.57
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Palbociclib Impurity-1

  • CAT NUMBER DCTI-C-2119
  • CAS NUMBER NA
  • MOLECULAR FORMULA C30H40BrN7O5
  • MOLECULAR WEIGHT 658.6
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Palbociclib Impurity-2

  • CAT NUMBER DCTI-C-2121
  • CAS NUMBER NA
  • MOLECULAR FORMULA C36H51N7O6
  • MOLECULAR WEIGHT 677.85
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Palbociclib Impurity-4

  • CAT NUMBER DCTI-C-2120
  • CAS NUMBER NA
  • MOLECULAR FORMULA C25H32BrN7O3
  • MOLECULAR WEIGHT 558.48
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Palbociclib Impurity-7

  • CAT NUMBER DCTI-C-2118
  • CAS NUMBER NA
  • MOLECULAR FORMULA C31H43N7O4
  • MOLECULAR WEIGHT 577.73
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Palbociclib N-boc Allyl Analog

  • CAT NUMBER DCTI-C-3002
  • CAS NUMBER 866084-31-3
  • MOLECULAR FORMULA C33H45N7O4
  • MOLECULAR WEIGHT 603.77
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References
FAQ's

References

  1. Barvian, Mark Robert; Booth, Richard John; Quin, John, III; Repine, Joseph Thomas; Sheehan, Derek James; Toogood, Peter Laurence; Vanderwel, Scott Norman; Zhou, Hairong, “2-(Pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones”, Warner-Lambert Company Llc, United States, US6936612B2, August 30, 2005
  2. Ma, Xingling; Liu, Lei; Cao, Na; Zou, Qiaogen; Xiong, Kaihe; Ouyang, Pingkai, “Isolation and structural elucidation of Palbociclib's eight process-related impurities: two identified as new compounds”, Journal of AOAC International, Volume: 99, Issue: 3, Pages: 638-648, 2016

Frequently Asked Questions

The potential sources of impurities in Palbociclib include starting materials, reagents, solvents, degradation products, and processing aids used during manufacturing.

Analytical methods such as HPLC, and LC-MS help identify and quantify Palbociclib impurities.

Impurities in Palbociclib are monitored during stability studies using validated analytical methods to ensure that the drug product remains within the specified limits over the shelf life of the product.

The recommended storage temperature for Palbociclib Impurities is 2-8°C in general. However, it depends upon the stability of the compound.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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