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Metoprolol
References
FAQ's
References
- Brandstrom, Arne E.; Carlsson, Per A. E.; Carlsson, Stig A. I.; Corrodi, Hans R.; Ek, Lars; Ablad, Bengt A. H., Phenoxyhydroxypropylamines and Their Preparation, Aktiebolaget Hassle, GB1308106A, February 28, 1973
- Zak, Sylvia; Honc, Frank; Gilleran, Thomas G., A sensitive gas chromatographic method for the determination of metoprolol in human plasma, Analytical Letters, Volume: 13, Issue: B15, Pages: 1359-71, 1980
Frequently Asked Questions
How are Metoprolol impurities detected and quantified?
Analytical Methods like reverse-phase ultra-performance liquid chromatographic method have been developed to estimate Metoprolol impurities quantitatively.
Can Metoprolol impurities affect patient safety?
Yes, impurities in Metoprolol can impact patient safety. Depending on their nature and concentration, contaminants can cause adverse effects or reduce the efficacy of the medication.
Which solvents help in the analysis of Metoprolol impurities?
Methanol is employed to attain the ideal solubility and differentiation of impurities in Metoprolol.
What are the temperature conditions required to store Metoprolol impurities?
Metoprolol impurities should generally be stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).
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