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If the presence of impurities in Ibuprofen is within acceptable limits, there is no cause for adverse effects or its impact on effectiveness. However, higher impurity levels could affect the drug's safety and efficacy.
While different brands of Ibuprofen may vary in manufacturing processes and quality control measures, all formulations must comply with regulatory standards for impurity levels. Therefore, the presence of impurities should be within acceptable limits regardless of the brand.
Acetonitrile or Methanol are the commonly used solvents when analyzing many impurities in Ibuprofen.
The recommendation is to store Ibuprofen impurities at a controlled room temperature, within 2-8 °C.
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