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Efinaconazole

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Efinaconazole Keto Impurity

  • CAT NUMBER DCTI-C-2692
  • CAS NUMBER 86404-63-9
  • MOLECULAR FORMULA C10H7F2N3O
  • MOLECULAR WEIGHT 223.18
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Efinaconazole-DCTI-C-497-Daicel
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Efinaconazole N-Oxide

  • CAT Number DCTI-C-497
  • CAS Number 2055038-63-4
  • Molecular Formula C18H22F2N4O2
  • Molecular Weight 364.4
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Enantiomer (2S,3R)-EFC-III

  • CAT NUMBER DCTI-C-1937
  • CAS NUMBER 135270-07-4
  • MOLECULAR FORMULA C12H11F2N3O
  • MOLECULAR WEIGHT 251.24
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References
FAQ's

References

  1. Naito, Takanobu; Kobayashi, Haruhito; Ogura, Hironobu; Nagai, Kiyoshi; Nishida, Tokiko; Arika, Tadashi; Yokoo, Mamoru; Nakahashi, Satoko, Azolylamine Derivative, Kaken Pharmaceutical Co., Ltd., Japan, EP698606B1, December 17, 1997
  2. Patani, Nikesh; Patel, Mrunali ; Patel, Rashmin, Development and validation of HPLC methodology for quantitative estimation of Efinaconazole in topical pharmaceutical formulation prepared in-house for the treatment of onychomycosis, Separation Science plus, Volume: 3, Issue: 9, Pages: 375-383, 2020

Frequently Asked Questions

Yes, impurities in Efinaconazole undergo comprehensive toxicological evaluations to determine their potential toxicity and establish safe exposure limits. This assessment ensures patient safety during drug administration.

Some impurities in Efinaconazole can impact its stability over time, potentially leading to degradation or reduced shelf life. Stability studies assess the drug's integrity under various storage conditions.

Impurity profiles for Efinaconazole are regularly reviewed and updated to align with evolving regulatory guidelines, scientific advancements, and emerging safety concerns. These updates help ensure the drug's continued quality and safety.

Efinaconazole impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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