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Dexmedetomidine

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Dexmedetomidine-DCTI-C-466-Daicel
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Dexmedetomidine Potential impurity-7 (Mixture of isomers)

  • CAT Number DCTI-C-466
  • CAS Number NA
  • Molecular Formula C13H23ClN2 (HCl Salt) C13H22N2 (Free Base)
  • Molecular Weight 249.79 (HCl Salt) 206.33 (Free Base)
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Dexmedetomidine-DCTI-C-458-Daicel
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Dexmedetomidine Potential Impurity-8

  • CAT Number DCTI-C-458
  • CAS Number 2250243-24-2
  • Molecular Formula C15H20N2
  • Molecular Weight 228.34
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Dibromomedetomide impurity
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Dibromomedetomide impurity

  • CAT Number DCTI-C-2210
  • CAS Number NA
  • Molecular Formula C13H14Br2N2
  • Molecular Weight 358.08
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Triphenylmethane impurity
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Triphenylmethane impurity

  • CAT Number DCTI-C-2070
  • CAS Number 519-73-3
  • Molecular Formula C19H16
  • Molecular Weight 244.34
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References
FAQ's

References

  1. Karjalainen, Arto Johannes; Virtanen, Raimo Einari; Savolainen, Eino Juhani, Optical Isomers Of An Imidazole Derivative, Farmos-Yhtyma Oy, Finland, GB2206880B, April 24, 1991
  2. Hui, Y.-H.; Marsh, K. C.; Menacherry, S., Analytical method development for the simultaneous quantitation of dexmedetomidine and three potential metabolites in plasma, Journal of Chromatography A, Volume: 762, Issue: 1 + 2, Pages: 281-291, 1997
  3. Ji, Qin C.; Zhou, Julie Y.; Gonzales, R. John; Gage, Eric M.; El-Shourbagy, Tawakol A., Simultaneous quantitation of dexmedetomidine and glucuronide metabolites (G-Dex-1 and G-Dex-2) in human plasma utilizing liquid chromatography with tandem mass spectrometric detection, Rapid Communications in Mass Spectrometry, Volume: 18, Issue: 15, Pages: 1753-1760, 2004

Frequently Asked Questions

Dexmedetomidine impurities help ensure the drug's quality, safety, and efficacy. Controlling impurities help maintain the desired pharmacological properties, reduces the risk of adverse effects, and ensures compliance with regulatory standards.

Impurities in Dexmedetomidine are analyzed using various analytical techniques such as chromatography (HPLC, LC), spectroscopy (UV, IR), mass spectrometry (MS), and other advanced methods. These techniques help in the identification, quantification, and characterization of impurities.

Methanol and Water are the solvents used in analyzing many impurities in Dexmedetomidine.

Dexmedetomidine impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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