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Methotrexate-DCTI-C-1413-daicelpharma
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Methotrexate Impurity I

API Category Methotrexate impurity
Appearance Hygroscopic Yellow Solid
CAT Number DCTI-C-1413
CAS Number 66147-29-3 (free base)
IUPAC Name (S)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-methoxy-5-oxopentanoic acid formate
Molecular Formula C21H24N8O5 (Free base) 22H26N8O7(Salt)
Molecular Weight 468.47 (Free base) 514.50 (Salt)
Solubility DMSO
Storage Condition 2-8°C
Synonyms Methotrexate EP Impurity I; Methotrexate EP Impurity I Formate salt

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(4-(Methylamino)benzoyl)-D-glutamic acid

  • CAT NUMBER DCTI-C-2595
  • CAS NUMBER 52030-86-1
  • MOLECULAR FORMULA C13H16N2O5
  • MOLECULAR WEIGHT 280.28

Methotrexate Impurity B

  • CAT Number DCTI-C-1412
  • CAS Number 54-62-6
  • Molecular Formula C19H20N8O5
  • Molecular Weight 440.41

(S)-5-ethoxy-2-(4-(methylamino)benzamido)-5-oxopentanoic acid

  • CAT NUMBER DCTI-C-3058
  • CAS NUMBER NA
  • MOLECULAR FORMULA C15H20N2O5
  • MOLECULAR WEIGHT 308.33

Methotrexate Impurity A

  • CAT NUMBER DCTI-C-1778
  • CAS NUMBER 945-24-4(Free Base) ; 73978-41-3(HCl Salt)
  • MOLECULAR FORMULA C7H8N6O (Free base) C7H9ClN6O (Salt)
  • MOLECULAR WEIGHT 192.18 (Free base) 228.64 (Salt)

Methotrexate-d3

  • CAT Number DCTI-A-244
  • CAS Number 432545-63-6
  • Molecular Formula C20H19D3N8O5
  • Molecular Weight 457.47

Methotrexate Impurity D

  • CAT Number DCTI-C-1283
  • CAS Number 5623-18-7
  • Molecular Formula C15H14N6O3
  • Molecular Weight 326.31

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