Valganciclovir

Sort by

2-amino-9-(methoxymethyl)-1,9-dihydro-6H-purin-6-one

  • CAT Number DCTI-C-1099
  • CAS Number 1202645-50-8
  • Molecular Formula C7H9N5O2
  • Molecular Weight 195.18

Chloro Diastereoisomer of Valganciclovir

  • CAT NUMBER DCTI-C-2175
  • CAS NUMBER 1654737-32-2 (Free Base)
  • MOLECULAR FORMULA C14H21ClN6O4 (Free base); C15H23ClN6O6 (Format Salt)
  • MOLECULAR WEIGHT 372.81 (Free base); 418.84 (Format Salt)

Isovalganciclovir

  • CAT Number DCTI-C-1071
  • CAS Number 1219792-42-3 (Free Base) ; 1429306-09-1 (HCl Salt)
  • Molecular Formula C14H22N6O5 (Free Base) C14H23ClN6O5(HCl Salt)
  • Molecular Weight 354.37 (Free Base) 390.82 (HCl Salt)

Mono des valine valganciclovir dimer

  • CAT Number DCTI-C-1100
  • CAS Number Na
  • Molecular Formula C24H35N11O9
  • Molecular Weight 621.61

Valganciclovir Dimer Impurity (Mixture of stereoisomers A, B & C)

  • CAT Number DCTI-C-1128
  • CAS Number 1401661-96-8
  • Molecular Formula C29H44N12O10
  • Molecular Weight 720.75

Valganciclovir N-Valyl Impurity

  • CAT NUMBER DCTI-C-2557
  • CAS NUMBER 897937-73-4
  • MOLECULAR FORMULA C19H31N7O6
  • MOLECULAR WEIGHT 453.5

General Information

Valganciclovir Impurities and Valganciclovir 

Daicel Pharma is a trusted provider of quality Valganciclovir impurity standards, including 2-amino-9-(methoxymethyl)-1,9-dihydro-6H-purin-6-one, Chloro Diastereoisomer of Valganciclovir, Isovalganciclovir, Mono des valine valganciclovir dimer, Valganciclovir Dimer Impurity (Mixture of stereoisomers A, B & C), and Valganciclovir N-Valyl Impurity. These impurities are crucial in meticulously evaluating the quality, stability, and safety of the active pharmaceutical ingredient, Valganciclovir. Furthermore, Daicel Pharma customizes Valganciclovir impurities, guaranteeing that it meets individual client specifications. With global shipping capabilities, they can be conveniently delivered to customers worldwide, offering unparalleled convenience.

Valganciclovir [CAS: 175865-60-8] is a L-valinyl ester of ganciclovir. It is an antiviral medication that treats cytomegalovirus (CMV) diseases. It effectively manages CMV retinitis in patients with AIDS.

Valganciclovir: Use and Commercial Availability

Valganciclovir is used to treat cytomegalovirus (CMV) retinitis, an eye infection that can occur in individuals with AIDS. It also helps prevent CMV disease in patients who have undergone organ transplantation. Valganciclovir is available under the brand name Valcyte.

Valganciclovir Structure and Mechanism of ActionValganciclovir Structure and Mechanism of Action

The chemical name of Valganciclovir is 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-Valine. Its chemical formula is C14H22N6O5, and its molecular weight is approximately 354.36 g/mol.

Valganciclovir is a prodrug of ganciclovir, consisting of a mixture of two diastereomers. Ganciclovir inhibits human cytomegalovirus replication.

Valganciclovir Impurities and Synthesis

Valganciclovir impurities can arise during synthesis1 due to the storage or use of specific raw materials and intermediates in manufacturing. These impurities encompass related compounds, degradation products, and process impurities. Stringent quality control measures and analytical methods are crucial to ensure the purity and safety of Valganciclovir for patient use.

Daicel Pharma provides a comprehensive Certificate of Analysis (CoA) for Valganciclovir impurity standards, such as 2-amino-9-(methoxymethyl)-1,9-dihydro-6H-purin-6-one, Chloro Diastereoisomer of Valganciclovir, Isovalganciclovir, Mono des valine valganciclovir dimer, Valganciclovir Dimer Impurity (Mixture of stereoisomers A, B & C), and Valganciclovir N-Valyl Impurity. The CoA includes detailed characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. Additionally, upon delivery, 13C-DEPT is also provided. Daicel possesses the technology and expertise to synthesize any unknown Valganciclovir impurity or degradation product.

References
FAQ's

Frequently Asked Questions

Yes, impurities in Valganciclovir undergo toxicity testing to assess their potentially harmful effects. The tests help determine their safety profile and establish acceptable limits to ensure patient safety.

Dimethyl sulfoxide (DMSO) and Acetonitrile are the solvents for analyzing many Valganciclovir impurities.

Reverse Phase-High-performance liquid chromatography (RP-HPLC) is employed to separate and analyze the impurities of Valganciclovir.

The recommendation is to store Valganciclovir impurities at room temperature, within 2-8 °C.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

Back to Top
Product has been added to your cart
jQuery(window).on('load', function() { $('input[name="productname"]').val($('.product_title').html()); });