Impurities in Sildenafil can affect its quality, safety, and efficacy. Depending on the type and level of impurities, they can impact the drug's pharmacological activity and stability and pose potential risks to patient health.

Impurities in Sildenafil are detected and quantified using analytical techniques such as HPLC-MS using Electrospray positive ionization. This method will allow for accurate identification and quantification of impurities.

Manufacturers can implement various measures to control impurity levels in Sildenafil, including using high-quality starting materials, optimizing synthesis and purification processes, conducting thorough quality control tests, and monitoring impurity levels throughout the manufacturing process.

Generally, Sildenafil Impurities are stored at a controlled room temperature between 2-8°C or as indicated on the Certificate of Analysis (CoA).