Sacubitril

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Sacubitril Impurity 4

  • CAT NUMBER DCTI-C-2401
  • CAS NUMBER 1012341-50-2
  • MOLECULAR FORMULA C23H29NO4
  • MOLECULAR WEIGHT 383.49

Sacubitril Lactum Impurity

  • CAT NUMBER DCTI-C-2972
  • CAS NUMBER NA
  • MOLECULAR FORMULA C22H23NO4
  • MOLECULAR WEIGHT 365.43

Sacubitril Maleic Impurity

  • CAT NUMBER DCTI-C-3141
  • CAS NUMBER 2751722-77-5
  • MOLECULAR FORMULA C24H27NO5
  • MOLECULAR WEIGHT 409.48

Sacubitril metabolite LBQ 657

  • CAT Number DCTI-A-107
  • CAS Number 149709-44-4
  • Molecular Formula C22H25NO5
  • Molecular Weight 383.44

Sacubitril metabolite LBQ 657 – D4 / Sacubitrilat/D4 (New)

  • CAT Number DCTI-A-108
  • CAS Number 149709-44-4(Unlabelled)
  • Molecular Formula C22H21D4NO5
  • Molecular Weight 387.47

Sacubitril methyl ester Impurity

  • CAT NUMBER DCTI-C-2400
  • CAS NUMBER 2408053-56-3
  • MOLECULAR FORMULA C23H27NO5
  • MOLECULAR WEIGHT 397.47

Succinamide impurity-(Sacubitril-Valsartan)

  • CAT NUMBER DCTI-C-2979
  • CAS NUMBER 1038924-97-8
  • MOLECULAR FORMULA C24H27NO4
  • MOLECULAR WEIGHT 393.48

tert-butyl (R)-(1-([1,1′-biphenyl]-4-yl)-3-b...

  • CAT NUMBER DCTI-C-3037
  • CAS NUMBER 1835193-08-2
  • MOLECULAR FORMULA C20H24BrNO2
  • MOLECULAR WEIGHT 390.32
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References
FAQ's

Frequently Asked Questions

The challenges associated with detecting and quantifying impurities in Sacubitril include its low level, the complex manufacturing process, and the usage of sensitive and specific analytical techniques. The variability of impurities between different batches of the drug can also be a challenge.

The Impurities in Sacubitril affect its stability and shelf life by promoting degradation reactions that reduce the drug’s potency over time. A few impurities also affect the physical properties of the drug, such as its solubility and crystallinity.

Methanol or Acetonitrile is the solvent used in analyzing many impurities in Sacubitril.

Sacubitril impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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