Pentoxifylline

Sort by

1,3,7- Trimethylxanthine-d3

  • CAT NUMBER DCTI-A-328
  • CAS NUMBER 72238-85-8
  • MOLECULAR FORMULA C8HD9N4O2
  • MOLECULAR WEIGHT 203.25

7-(Methyl-D3)-Xanthine

  • CAT NUMBER DCTI-A-324
  • CAS NUMBER 1185878-99-2
  • MOLECULAR FORMULA C6H3D3N4O2
  • MOLECULAR WEIGHT 169.16

Pentoxifylline D6

  • CAT NUMBER DCTI-A-337
  • CAS NUMBER 1185878-98-1
  • MOLECULAR FORMULA C13H12D6N4O3 (Free Base)
  • MOLECULAR WEIGHT 284.35 (Free Base)

Pentoxifylline Metabolite I

  • CAT NUMBER DCTI-C-2610
  • CAS NUMBER 6/7/6493
  • MOLECULAR FORMULA C13H20N4O3
  • MOLECULAR WEIGHT 280.33

Pentoxifylline Metabolite I-D6

  • CAT NUMBER DCTI-A-303
  • CAS NUMBER 1185995-26-9
  • MOLECULAR FORMULA C13H14D6N4O3
  • MOLECULAR WEIGHT 286.36

Pentoxifylline Metabolite V

  • CAT NUMBER DCTI-C-2609
  • CAS NUMBER 7/8/6493
  • MOLECULAR FORMULA C11H14N4O4
  • MOLECULAR WEIGHT 266.26

Pentoxifylline Metabolite V-d6

  • CAT NUMBER DCTI-A-302
  • CAS NUMBER 1246816-64-7
  • MOLECULAR FORMULA C11H8D6N4O4
  • MOLECULAR WEIGHT 272.29

General Information

Pentoxifylline Impurities and Pentoxifylline

Daicel Pharma offers Pentoxifylline impurity standards like Pentoxifylline Metabolite V and Pentoxifylline Metabolite I. The impurities can impact Pentoxifylline efficacy, stability, and safety. Daicel Pharma can synthesize Pentoxifylline impurities and deliver them worldwide.

Pentoxifylline [CAS: 6493-05-6] is a synthetic compound derived from dimethylxanthine that modifies blood flow while possessing both anti-oxidant and anti-inflammatory properties. It treats symptoms of intermittent claudication due to peripheral arterial disease.

Pentoxifylline: Use and Commercial Availability

Pentoxifylline treats patients with chronic occlusive artery disease who have intermittent claudication. It may enhance limb function and lessen discomfort but cannot replace other treatments, such as surgical bypass surgery. Pentoxifylline, a xanthine derivative, reduces blood viscosity. This medication is available under certain tradenames such as Pentoxil and Trental.

Pentoxifylline Structure and Mechanism of ActionPentoxifylline Structure and Mechanism of Action

The chemical name of Pentoxifylline is 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione. Its chemical formula is C13H18N4O3, and its molecular weight is approximately 278.31 g/mol.

Pentoxifylline decreases the viscosity of blood and improves blood flow properties.

Pentoxifylline Impurities and Synthesis

Impurities in Pentoxifylline can develop at several stages of the synthetic process1, such as incomplete reactions, side reactions, and contaminants in the raw materials and reagents. Depending on the individual impurity and the circumstances, different Pentoxifylline impurities can synthesize using methods.

Daicel Pharma offers a Certificate of Analysis (CoA) for Pentoxifylline impurity standards, such as Pentoxifylline Metabolite V and Pentoxifylline Metabolite I. We provide a Certificate of Analysis (CoA) from our cGMP-certified analytical lab, which includes extensive characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. Additional characterization information, including 13C-DEPT, can be provided upon request. Our team at Daicel Pharma specializes in offering Pentoxifylline impurities and degradation products. We offer Pentoxifylline Metabolite V-d6, Pentoxifylline Metabolite I-D6, 7-(Methyl-D3)-Xanthine, and 1,3,7- Trimethylxanthine-d3, highly pure deuterium-labeled Pentoxifylline compounds, valuable for bioanalytical research and Bioavailability/Bioequivalence (BA/BE) researches.

References
FAQ's

Frequently Asked Questions

Pentoxifylline impurities are reduced but not removed.

Analyzing Pentoxifylline impurities is significant for ensuring safety, efficacy, and quality, as it can impact its effectiveness and pose potential risks to patients.

Pentoxifylline impurities are synthesized through various pathways during the synthetic process, including incomplete reactions, side reactions, and their presence in starting materials or reagents.

Pentoxifylline impurities are stored at a regulated room temperature of 2-8°C or as specified on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

Back to Top
Product has been added to your cart
jQuery(window).on('load', function() { $('input[name="productname"]').val($('.product_title').html()); });