General Information

Nitroso Compounds Impurities and Nitroso Compounds 

Daicel Pharma offers Nitroso Compounds impurities, including 1-nitroso-1,2,3,6-tetrahydropyridine, 2-Nitro-diphenylamine (NDPA), N-methyl-N-nitrosophenethylamine, N-Nitroso Dabigatran etexilate, N-Nitroso Mirabegron, N-Nitroso N-Desbenzyl Nicardipine Impurity, Palbociclib Nitroso Impurity, N-Nitroso Rasagiline, N-(2-(ethyl(nitroso)amino)ethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide, N-Nitroso Tigecycline, and more. These impurities are essential for evaluating the quality, stability, and safety of Nitroso Compounds. Furthermore, Daicel Pharma offers custom synthesis of Nitroso Compounds impurities and distributes them internationally to fulfill the clientele’s needs.

Nitroso Compounds have varied applications, including intermediates in organic synthesis, catalysts, and pharmaceutical agents.

Nitroso Compounds: Use and Commercial Availability 

Nitroso compounds can be useful as intermediates in synthesizing pharmaceuticals, agrochemicals, dyes, and other chemical compounds. They can also act as catalysts in chemical reactions. Nitroso Compounds are available under the Monograph System governed by OTC Monographs and Administrative Orders.

Nitroso Compounds Impurities and Synthesis

Nitroso Compounds impurities refer to unwanted substances that arise during the synthetic process or storage and may include unreacted starting materials, by-products, or degradation products. The control and monitoring of impurities assure the quality, safety, and efficacy of Nitroso Compounds. The synthesis of Nitroso Compounds involves various methods depending on the specific compound desired.

Daicel provides a Certificate of Analysis (CoA) for Nitroso Compound impurity standards, including 1-nitroso-1,2,3,6-tetrahydropyridine, 2-Nitro-diphenylamine(NDPA), and N-methyl-N-nitrosophenethylamine that can be present in Nitroso Compounds. Also, Nitroso impurity standards like N-Nitroso Dabigatran etexilate, N-Nitroso Mirabegron, N-Nitroso N-Desbenzyl Nicardipine Impurity, Palbociclib Nitroso Impurity, N-Nitroso Rasagiline, N-(2-(ethyl(nitroso)amino)ethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide, N-Nitroso Tigecycline, and more. Our cGMP-compliant analytical laboratory offers the CoA, which contains extensive characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity¹. We give additional characterization data, such as 13C-DEPT, on request. Daicel Pharma can synthesize unknown Nitroso Compound impurities or degradation products and deliver labeled compounds to test the efficacy of generic Nitroso Compounds. Each shipment includes a detailed characterization report. Daicel Pharma offers N-Nitroso-N-methyl-4-aminobutyric Acid-d3, Sitagliptin Nitroso Impurity-D4, Nitroso Nebivolol D4, Trimetazidine nitroso D9 impurity, etc., deuterium-labeled Nitroso compound standards for bioanalytical research and BA/BE testing.