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Levothyroxine

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Levothyroxine-DCTI-C-188-Daicel
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Monochlorotriiodothyronine (Impurity-B)

  • CAT Number DCTI-C-188
  • CAS Number 1628720-66-0
  • Molecular Formula C15H11ClI3NO4
  • Molecular Weight 685.42
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Levothyroxine-DCTI-C-281-Daicel
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N-acetyl-L-thyroxine

  • CAT Number DCTI-C-281
  • CAS Number 26041-51-0
  • Molecular Formula C17H13I4NO5
  • Molecular Weight 818.91
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Levothyroxine-DCTI-C-195-Daicel
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T4-acetamide

  • CAT Number DCTI-C-195
  • CAS Number 176258-88-1
  • Molecular Formula C14H9I4NO3
  • Molecular Weight 746.85
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Levothyroxine-DCTI-C-482-Daicel
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T4-Acetic acid impurity

  • CAT Number DCTI-C-482
  • CAS Number 67-30-1
  • Molecular Formula C14H8I4O4
  • Molecular Weight 747.83
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Levothyroxine-DCTI-C-191-Daicel
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T4-Aldehyde (Impurity-I)

  • CAT Number DCTI-C-191
  • CAS Number 2016-06-0
  • Molecular Formula C13H6I4O3
  • Molecular Weight 717.81
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Levothyroxine-DCTI-C-196-Daicel
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T4-amine-O-methyl

  • CAT Number DCTI-C-196
  • CAS Number 2230724-39-5
  • Molecular Formula C15H14ClI4NO2
  • Molecular Weight 783.35
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Levothyroxine-DCTI-C-194-Daicel
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T4-Hydroxy acetic acid

  • CAT Number DCTI-C-194
  • CAS Number 93647-48-4
  • Molecular Formula C14H8I4O5
  • Molecular Weight 763.83
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T4-Lactic acid

  • CAT NUMBER DCTI-C-2057
  • CAS NUMBER 7069-47-8
  • MOLECULAR FORMULA C15H10I4O5
  • MOLECULAR WEIGHT 777.86
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Triiodothyronine sulfate

  • CAT NUMBER DCTI-C-2254
  • CAS NUMBER 31135-55-4
  • MOLECULAR FORMULA C15H12I3NO7S
  • MOLECULAR WEIGHT 731.03
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References
FAQ's

References

 

  1. Nishinaga, Akira; Kon, Hideo; Cahnmann, Hans J.; Matsuura, Teruo, Model reactions for the biosynthesis of thyroxine. XI. Nature of a free radical formed in the autoxidation of 4-hydroxy-3,5-diiodophenylpyruvic acid, Journal of Organic Chemistry, Volume: 33, Issue: 1, Pages: 157-62, 1968
  2. Hathaway, James A.; Sannella, Joseph J.; Hunter, DeWitt T. Jr., Thyroxine determination by continuous spectrophotometry, American Journal of Clinical Pathology, Volume: 53, Issue: 5, Pages: 635-40, 1970
 

Frequently Asked Questions

Higher levels of impurities in Levothyroxine may impact its therapeutic response, efficacy, or consistency, necessitating strict control measures during manufacturing.

Some Levothyroxine impurities may undergo chemical transformations or degradation during storage, which can affect the overall purity and stability of the drug.

Some impurities may interfere with the pharmacokinetics or pharmacodynamics of Levothyroxine, potentially impacting its interactions with other medicines.

Levothyroxine impurities should be stored at a controlled room temperature, usually between 2-8 °C.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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