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Eliglustat

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Eliglustat-DCTI-C-173-Daicel
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Eliglustat O-Octanyl Impurity

  • CAT Number DCTI-C-173
  • CAS Number 2193052-06-9
  • Molecular Formula C31H50N2O5
  • Molecular Weight 530.75
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Eliglustat-DCTI-C-481-Daicel
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N-Acetyl impurity(Eliglustat)

  • CAT Number DCTI-C-481
  • CAS Number 2219353-50-9
  • Molecular Formula C17H24N2O4
  • Molecular Weight 320.39
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References
FAQ's

References

  1. Hirth, Bradford H.; Siegel, Craig, A N-Acylsphingosine Glucosyltransferase Inhibitor, Genzyme Corporation, United States, EP1409467B1, April 18, 2012
  2. Umamaheshwar Puppala,Koduri S V Srinivas,K Venkateshwara Reddy,Muralidharan Kaliyaperumal,Raju Doddipalla &Bhaskar Rao Jogi, Isolation and Characterization of Novel Degradation Products of Eliglustat Tartrate Using 2D-NMR and HRMS: Development and Validation of Stability Indicating RP-UPLC Method for Quantification of Assay and Characterized Impurities, Analytical Chemistry Letters,Volume 10, 2020 - Issue 1, Pages 1-20

Frequently Asked Questions

The formation of Eliglustat impurities is minimized by optimizing reaction conditions, employing suitable purification techniques, ensuring proper storage and handling, and conducting stability studies to understand degradation pathways.

Impurities in Eliglustat can potentially impact its efficacy by altering the drug's pharmacokinetics, stability, or interaction with the target receptors. Hence, their control is essential to maintain the desired therapeutic effect.

Analyzing Eliglustat impurities can be challenging due to their low concentrations, potential complexity, and the need for sensitive and specific analytical techniques. Validation of analytical methods is crucial for accurate impurity detection.

Eliglustat impurities are stored at a controlled room temperature, 2-8 °C, or under a Nitrogen atmosphere. You can refer to the storage on the Certificate of Analysis (CoA) specifications.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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