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Edoxaban

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N-Des Methyl Edoxaban coupled
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N-Des Methyl Edoxaban coupled

  • CAT Number DCTI-C-876
  • CAS Number NA
  • Molecular Formula C31H36ClN9O5S2
  • Molecular Weight 714.26
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N-Des Methyl Edoxaban hydrochloride
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N-Des Methyl Edoxaban hydrochloride

  • CAT Number DCTI-C-875
  • CAS Number 778571-11-2 (Free base) 480449-52-3 (HCl salt)
  • Molecular Formula C23H28ClN7O4S (Free Base) C23H28ClN7O4S . ClH (Salt)
  • Molecular Weight 534.03 (Free Base) 570.49 (HCl Salt)
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References
FAQ's

References

  1. Ohta, Toshiharu; Komoriya, Satoshi; Yoshino, Toshiharu; Uoto, Kouichi; Nakamoto, Yumi; Naito, Hiroyuki; Mochizuki, Akiyoshi; Nagata, Tsutomu; Kanno, Hideyuki; Haginoya, Noriyasu; et al, Diamine Derivatives, Daiichi Pharmaceutical Co., Ltd., Japan, EP1405852B1, August 1, 2012
  2. He, Ling; Kochan, Jarema; Lin, Min; Vandell, Alexander; Brown, Karen; Depasse, Francois, Determination of edoxaban equivalent concentrations in human plasma by an automated anti-factor Xa chromogenic assay, Thrombosis Research, Volume: 155,Pages: 121-127, 2017

Frequently Asked Questions

Yes, impurities in Edoxaban are closely monitored during clinical trials to assess their impact on safety, efficacy, and patient tolerability. Any significant impurities are thoroughly evaluated and controlled.

Certain impurities in Edoxaban may have the potential to interact with other medications. Drug-drug interaction studies help evaluate such possibilities and ensure safe co-administration.

Storage conditions can influence the formation of impurities in Edoxaban. Proper storage, including temperature control and protection from light and moisture, is essential to minimize impurity formation.

Edoxaban impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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