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Cisatracurium

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Cisatracurium-DCTI-C-1271-Daicel
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Cisatracurium EP impurity-F

  • CAT Number DCTI-C-1271
  • CAS Number 1100676-16-1
  • Molecular Formula C35H47NO10S (Salt) C29H42NO7(Free base)
  • Molecular Weight 673.82 (Salt) 516.65 (Free base)
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Cisatracurium-DCTI-C-1272-Daicel
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Cisatracurium EP impurity-N

  • CAT Number DCTI-C-1272
  • CAS Number NA
  • Molecular Formula C38H49NO11S (Salt) C32H44NO8 (Free base)
  • Molecular Weight 727.87 (Salt) 570.70 (Free base)
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Cisatracurium EP Impurity-O

  • CAT NUMBER DCTI-C-2257
  • CAS NUMBER 2803857-41-0 (free base)
  • MOLECULAR FORMULA C32H44NO8 (free base) ; C38H49NO11S (salt)
  • MOLECULAR WEIGHT 570.70 (free base) ; 727.87 (salt)
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Cisatracurium-DCTI-C-1273-Daicel
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Cisatracurium EP impurity-R

  • CAT Number DCTI-C-1273
  • CAS Number NA
  • Molecular Formula C55H70N2O20 (Salt) C51H66N2O12 (Free base)
  • Molecular Weight 1079.16 (Salt) 899.09 (Free base)
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Cisatracurium-DCTI-C-1274-Daicel
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Cisatracurium EP impurity-W

  • CAT Number DCTI-C-1274
  • CAS Number 2411761-85-6 (Free acid)
  • Molecular Formula C37H49NO11S (Salt) C31H44NO8 (Free base)
  • Molecular Weight 715.85 (Salt) 558.69 (Free base)
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References
FAQ's

References

  1. Hill, Derek A.; Turner, Geoffrey L., Neuromuscular blocking agents, Burroughs Wellcome Co., United States, US5453510A, Sep 26, 1995
  2. Bryant, B. J.; James, Charles D. Jr.; Cook, D. Ryan; Harrelson, Jane Croft, High performance liquid chromatographic assay for cisatracurium and its metabolites in human urine, Journal of Liquid Chromatography & Related Technologies, Volume: 20, Issue: 13, Pages: 2041-2051, 1997
  3. Gao, Jieying; Yang, Ting; Ye, Mao; Zhang, Xiaoqing; Tian, Gang; Zhen, Qianna; Ding, Min, High-performance liquid chromatography assay with programmed flow elution for cisatracurium in human plasma: Application to pharmacokinetics in infants and children, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Volume: 955-956, Pages: 58-63, 2014

Frequently Asked Questions

Synthesizing Cisatracurium impurities helps identify and quantify the impurities present in Cisatracurium besylate, a neuromuscular blocking agent used during surgery. It is essential for quality control and ensuring the safety and efficacy of the drug.

The detection and quantification of Cisatracurium impurities typically involve analytical techniques such as high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), etc.

Methanol, DCM (Dichloromethane), or DMSO (Dimethyl sulfoxide) are the solvents used based on the impurity profile of Cisatracurium and its impurities.

Cisatracurium impurities storage is at a controlled room temperature between 2-8 ⁰C. However, impurities such as Cisatracurium Besylate EP Impurity-Q are stored at -20 ⁰C as per the stability of the compound.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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