Apixaban

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Apixaban Open Ring Amide Impurity

  • CAT NUMBER DCTI-C-3269
  • CAS NUMBER 2187409-01-2
  • MOLECULAR FORMULA C25H28N6O4
  • MOLECULAR WEIGHT 476.54

APX-Methoxy chlorohydrazone

  • CAT NUMBER DCTI-C-2903
  • CAS NUMBER NA
  • MOLECULAR FORMULA C12H16N2O4
  • MOLECULAR WEIGHT 252.27

ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-...

  • CAT NUMBER DCTI-C-2295
  • CAS NUMBER 536759-91-8
  • MOLECULAR FORMULA C22H20N4O6
  • MOLECULAR WEIGHT 436.42

ethyl 1-(4-methoxyphenyl)-7a-morpholino-6-(4-nitro...

  • CAT NUMBER DCTI-C-2300
  • CAS NUMBER 1620386-62-0
  • MOLECULAR FORMULA C58H71Cl2N8O15
  • MOLECULAR WEIGHT 1191.15

ethyl 2-chloro-2-(2-(4-hydroxyphenyl)hydrazineylidene)acetate

  • CAT NUMBER DCTI-C-2296
  • CAS NUMBER NA
  • MOLECULAR FORMULA C10H11ClN2O3
  • MOLECULAR WEIGHT 242.66

Ethyl 6-(4-(5-bromopentanamido)phenyl)-1-(4-methox...

  • CAT NUMBER DCTI-C-2297
  • CAS NUMBER 881386-12-5
  • MOLECULAR FORMULA C27H29BrN4O5
  • MOLECULAR WEIGHT 569.46

ethyl 6-(4-(5-chloropentanamido)phenyl-1-(4-methox...

  • CAT NUMBER DCTI-C-2298
  • CAS NUMBER 1421823-20-2
  • MOLECULAR FORMULA C27H29ClN4O5
  • MOLECULAR WEIGHT 525

ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-...

  • CAT NUMBER DCTI-C-2299
  • CAS NUMBER 503615-07-4
  • MOLECULAR FORMULA C22H22N4O4
  • MOLECULAR WEIGHT 406.44

Hydroxy Apixaban

  • CAT NUMBER DCTI-C-3008
  • CAS NUMBER 503612-76-8
  • MOLECULAR FORMULA C24H23N5O4
  • MOLECULAR WEIGHT 445.48
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References
FAQ's

Frequently Asked Questions

Impurity profiling is a critical step in Apixaban manufacturing as it helps identify, characterize, and quantify impurities present in the drug substance. It helps to optimize the manufacturing process and ensure the drug’s quality, safety, and efficacy.

Common impurities found in Apixaban include degradation products and residual solvents and may result from the manufacturing process, such as unreacted starting materials, reagents, or by-products.

Apixaban impurities are removed through purification steps such as recrystallization, distillation, or chromatography.

Apixaban impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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