Tamsulosin - NDSRI's
References
- Niigata, Kunihiro; Fujikura, Takashi, Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them, Yamanouchi Pharmaceutical Co., Ltd., US4731478A, March 15, 1988
- Matsushima, Hiroshi; Takanuki, Ken-ichi; Kamimura, Hidetaka; Watanabe, Takashi; Higuchi, Saburo, Highly sensitive method for the determination of tamsulosin hydrochloride in human plasma dialyzate, plasma and urine by high-performance liquid chromatography-electrospray tandem mass spectrometry, Journal of Chromatography B: Biomedical Sciences and Applications, Volume: 695, Issue: 2, Pages: 317-327, 1997
Frequently Asked Questions
How are Tamsulosin impurities detected and quantified?
Impurities in Tamsulosin can be detected using analytical techniques like High-Performance Liquid Chromatography (HPLC).
Can Tamsulosin impurities affect patient safety?
The presence of impurities in Tamsulosin can affect patient safety. The type and level of these impurities can lead to adverse effects or diminish the effectiveness of the medication.
Which solvents help in the analysis of Tamsulosin impurities?
Acetonitrile is used to achieve optimal solubility and separation of Tamsulosin impurities.
5. What are the temperature conditions required to store Tamsulosin impurities?
Tamsulosin impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).
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