Sacubitril - NDSRI's

Sacubitril Maleic Impurity

  • CAT NUMBER DCTI-C-3141
  • CAS NUMBER 2751722-77-5
  • MOLECULAR FORMULA C24H27NO5
  • MOLECULAR WEIGHT 409.48
References
FAQ's

Frequently Asked Questions

The challenges associated with detecting and quantifying impurities in Sacubitril include its low level, the complex manufacturing process, and the usage of sensitive and specific analytical techniques. The variability of impurities between different batches of the drug can also be a challenge.

The Impurities in Sacubitril affect its stability and shelf life by promoting degradation reactions that reduce the drug’s potency over time. A few impurities also affect the physical properties of the drug, such as its solubility and crystallinity.

Methanol or Acetonitrile is the solvent used in analyzing many impurities in Sacubitril.

Sacubitril impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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