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Apixaban - NDSRI's
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1-(4-hydroxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-y...

  • CAT NUMBER DCTI-C-3026
  • CAS NUMBER 2459302-74-8
  • MOLECULAR FORMULA C24H22N4O5
  • MOLECULAR WEIGHT 446.16
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3-acetyl-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-1,4...

  • CAT NUMBER DCTI-C-3107
  • CAS NUMBER NA
  • MOLECULAR FORMULA C21H18N4O5
  • MOLECULAR WEIGHT 406.4
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References
FAQ's

References

  1. Pinto, Donald; Quan, Mimi; Orwat, Michael; Li, Yun-Long; Han, Wei; Qiao, Jennifer; Lam, Patrick; Koch, Stephanie, Lactam-Containing Compounds And Derivatives Thereof As Factor Xa Inhibitors, Bristol-Myers Squibb Company, United States, EP1427415B1, August 12, 2009
  2. Delavenne, Xavier; Mismetti, Patrick; Basset, Thierry, Rapid determination of apixaban concentration in human plasma by liquid chromatography/tandem mass spectrometry: Application to pharmacokinetic study, Journal of Pharmaceutical and Biomedical Analysis, Volume: 78-79, Pages: 150-153, 2013

Frequently Asked Questions

Impurity profiling is a critical step in Apixaban manufacturing as it helps identify, characterize, and quantify impurities present in the drug substance. It helps to optimize the manufacturing process and ensure the drug’s quality, safety, and efficacy.

Common impurities found in Apixaban include degradation products and residual solvents and may result from the manufacturing process, such as unreacted starting materials, reagents, or by-products.

Apixaban impurities are removed through purification steps such as recrystallization, distillation, or chromatography.

Apixaban impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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